Monday, May 18, 2020

Gene Mutation A Sequence Of Numbers - 1882 Words

It all starts off as a big puzzle, you have all these pieces that connect together that leads to a sequence of numbers. These numbers may be in order and fit perfectly into your puzzle, but then there is that one out of place piece that makes the puzzle not complete, that essentially is what the BRCA 1 gene mutation is, just a misplaced puzzle piece. The BRCA 1 gene mutation can go by many names like breast cancer 1, early onset or IRIS, but no matter what name you call it, it still inflicts some questions and concerns. The BRCA 1 gene mutation is a human gene that produces tumor suppressor proteins located on chromosome 17 at position 21. These proteins when not mutated, help repair damaged DNA and play a role in ensuring the stability of one s cellular genetic material. When the gene becomes mutated, faulty, or altered it has the reverse effects. The protein sometimes does not form or forms incorrectly, therefore leading to DNA damage that may not be repaired properly. This results in an unfinished puzzle piece, which leads to the development of genetic alterations, in other words, could increase your risks of certain cancers. The BRCA 1 gene mutation is just like all other genes is inherited and passed on by your family, but it does not mean you will have the mutation. The BRCA 1 gene mutation can be inherited from either of your parents when one of your parents carries the mutation you have a fifty percent chance of inheriting the mutation. If you do inherit thisShow MoreRelatedBLAT Analysis On Biology1298 Words   |  6 PagesBLAST analysis on your allocated sequence and answer the following questions based on the results. Plagarism will result in an automatic score of zero. 1. Identify the gene 5% Homo sapiens cytochrome P450 family 24 subfamily A member 1 (CYP24A1), transcript variant X3, mRNA 2. Show the results of your BLAST analysis obtained at both nucleotide (2%) and protein (2%) level and identify the types of mutation(s) present (6%). You should also highlight where the mutations occur on the copied alignmentsRead MoreThe Change Of Hemoglobin Changes Essay1210 Words   |  5 Pagesas the change in the oxygen in the environment occurs. Each globin usually has two polypeptide chains encoded by genes that attract oxygen molecules to different degrees. 2. The pancreas which has two types of cell clusters. A transcription factor is activated and change the expression of a gene in a way that stimulates some progenitor cells to divide. 3. Proteomics is an area where gene expression emerges. It identifies and analyzes all the proteins that made in a cell, organ, or body. 4. The histoneRead MoreDna Analysis : Cracking Your Genetic Code866 Words   |  4 Pagesdetermine the nucleotide sequence. Over the time various methods have been developed to obtain the nucleotide sequence of DNA, currently the most widely used methods include automated sequencing and enzymatic chain termination. During this Case Study I will explain what a genetic mutation is and the difference between inherited mutations versus point mutations, I will also describe how the technology explained in Cracking Your Genetic Code can be used to detect mutations and predict your healthRead MoreDna Repair Mechanisms And Cell Cycle Control988 Words   |  4 PagesSaccharomyces cerevisiaes, or baker’s yeasts, unicellular fungi are useful in understanding genetics and molecular biology, due to the ability to quickly map a phenotype-producing gene to a region in their genome. Yeast mutants are used a tool for the study of cellular function, DNA repair mechanisms and cell cycle contro l. As a model organism, S. cerevisiae is one of the simplest eukaryote organism, having not only most major signaling pathways conserved, but also consisting of a genome of approximatelyRead MoreMouse Model And Sample Size935 Words   |  4 Pagesmice will be selected as they are double mutants; they will have undergone an exon 7 deletion in their SMN1 gene resulting in the development of SMA, and they will have a human SMN2 transgene, since mice do not normally have SMN2 genes. The mice will be homozygous for the SMN1 with the knockout, this is important because over 95% of SMA cases are due to the homozygous deletion of SMN1 genes. They will also be homozygous for the SMN2 transgene as SMN2 hemizygous mice do not survive past 16 days postnatalRead MoreProposed Genetic Algorithm Of Protein Tertiary Structure Prediction Essay1748 Words   |  7 Pagesoperations of recombination and mutation to create a new offspring population from the current population. The process evolution usu ally starts from a population of randomly generated individuals or, using domain background knowledge. The generation process repeats for many generations with the aim of maximizing the objective Function (also called fitness) of the chromosomes that are evaluated each generation. Usually, the GA termination cindition are set to the maximum number of generations. ii) GeneticRead MoreCase Study : ÃŽÂ’ -thalassemia1717 Words   |  7 Pagesare a heterogeneous group of hereditary anemias that constitute the most common gene disorder in the world, with a carrier rate of almost 7%. The disease was first discovered in countries around the Mediterranean Sea and was named for the Greek word â€Å"Thalassa,† meaning â€Å"sea.† However, it is also present in areas extending into India and China that are near the Equator. The thalassemia syndromes are caused by mutations that decrease or abolish the synthesis of the ÃŽ ±- or ÃŽ ²-chains in the adult hemoglobinRead MoreRecent Developments Of Gene Editing Technology And Their Potential Applications For Plants And Agriculture1338 Words   |  6 Pagesand inefficient methods such as artificial selection and mutation breeding. Now the ability to tailor the fundamental genetics of plants through precise gene modification is possible allowing control of the biological mechanisms present. Increasing the efficiency of the growth and maintenance of plants through gene modification could save vast amounts of money and resources. In this essay I will be discussing the recent developments in gene editing technology and their potential applications to plantsRead MoreThe Human Genome And The Building Blocks Of Life1359 Words   |  6 PagesRaul Santos 7-8 Period 4/9/2015 Genetics Much research has gone into learning about the human genome and the building blocks of life. Thanks to genetic research we have learned about mutations and what medical effects they can have on a person. Genetic research allows us to better understand and genetic variation. It has made easier the process of mass producing crops. Because of how useful genetic research is, billions of dollars have been invested in it by companies around the world. But what exactlyRead MoreWhat Is Familiarization And Planning For Sanger Sequencing760 Words   |  4 Pagesplanning for Sanger Sequencing it is important to become familiar with a number of aspects of the gene of interest as it relates to the disease(s) caused by mutations in that gene. †¢ Identification of the reference sequence to be used for comparison of test sequence data. These sequences are typically obtained from the National Center for Biotechnology Information (NCBI; http://www.ncbi.nlm.nih.gov/ with the date of access). Many genes have alternative transcripts and promoters that should be taken into

Monday, May 11, 2020

How The Nursery Rhyme Eins, Zwei, Polizei Can Help You Learn German

Learning German can a lot of fun if you use a simple rhyme. While Eins, Zwei, Polizei is a nursery rhyme for children, people of any age can use it as a game to expand their German vocabulary. This short rhyme is a traditional childrens song that can be sung or chanted to a beat. It includes very basic German words, teaches you how to count to ten or fifteen (or higher, if you like), and each phrase ends with a different word.   There are many versions of this popular and simple song and two of those are included below. However, dont stop with those. As you will see, you can make up your own verses and use this as a game to practice whatever vocabulary words you are learning at the moment. Eins, zwei, Polizei (One, Two, Police) This is the most traditional version of the popular German childrens song and  nursery rhyme. It is very easy to memorize and will help you remember numbers one through ten along with a few basic words. Both children and adults will find it to be a fun way to finish off your night with a little German practice.   This version of Eins, zwei, Polzei has been recorded by at least two German groups: Mo-Do (1994) and S.W.A.T. (2004). While the lyrics for the song by both groups are appropriate for children, the rest of the albums may not be. Parents should review the translations for themselves before playing the other songs for kids. Melodie: Mo-DoText: Traditional   Deutsch English Translation Eins, zwei, Polizeidrei, vier, Offizierfnf, sechs, alte Hexsieben, acht, gute Nacht!neun, zehn, auf Wiedersehen! One, two, policethree, four, officerfive, six, old witchseven, eight, good night!nine, ten, good-bye! Alt. verse:neun, zehn, schlafen gehn. Alt. verse:nine, ten, off to bed. Eins, zwei, Papagei (One, Two, Parrot) Another variation that follows the same tune and rhythm, Eins, zwei, Papagei demonstrates how you can change the last word of each line to fit the German words and phrases you are learning at the moment. As you can see, it doesnt have to make sense, either. In fact, the less sense it makes, the funnier it is. Deutsch English Translation Eins, zwei, Papageidrei, vier, Grenadierfnf, sechs, alte Hexsieben, acht, Kaffee gemachtneun, zehn, weiter gehnelf, zwlf, junge Wlfdreizehn, vierzehn, Haselnussfnfzehn, sechzehn, du bist duss. One, two, Parrotthree, four, Grenadier*five, six, old witchseven, eight, made coffeenine, ten, go furthereleven, twelve, young wolfthirteen, fourteen, Hazelnutfifteen, sixteen, youre dumb. * A  Grenadier  is similar to a private or infantryman in the military. It is understandable if you do not want to teach your children this last version (or at least the last line), which includes the words du bist duss because it translates to youre dumb. Its not very nice and many parents choose to avoid such words, particularly in nursery rhymes with younger children. Instead of avoiding this otherwise fun rhyme, consider replacing the last part of that line with one of these more positive phrases: Youre great - du bist tollYoure funny - du bist lustigYoure pretty - du bist hà ¼bschYoure handsome - du bist attraktivYoure smart - du bist shlauYoure special - du bist etwas  Besonderes How Eins, zwei... Can Expand Your Vocabulary Hopefully, these two examples of the rhyme will inspire you to use it throughout your studies of German. Repetition and rhythm are two useful techniques that will help you remember basic words and this is one of the easiest songs to do that with. Make a game out of this song, either on your own, with your study partner, or with your children. It is a fun and interactive way to learn. Alternate saying each line between two or more people.Complete each phrase with a new (and random) word from your most recent vocabulary list. It can be anything from food and plants to people and objects, whatever you think of. See if the other players know what that word means in English.Practice two- or three-word phrases on the last line.Count as high as you can and keep finishing off each line with a new word. See who can count the highest in German or who can say more  new words than everyone else.Try to create a theme throughout the song. Maybe your family is learning the German words for various fruits (Frà ¼chte). One line might finish with apple (Apfel), the next might end with pineapple (Ananas), then you might say strawberry (Erdbeere), and so on. This is one rhyme that has endless possibilities and it can really help you  learn the German language. Its hours (or minutes) of fun and can be played anywhere.

Wednesday, May 6, 2020

The Final Step In Stopping Isis In The Middle East Is To

The final step in stopping ISIS in the Middle East is to stabilize the countries in which they gained their power, Iraq and Syria. By looking at what caused the destabilization in the first place will allow for a better understanding of the policies and actions that need to be put in place in order to move the conflict toward de-escalation. Transparency International explains, â€Å"when disenfranchised populations see [†¦] their governments fail to deliver services, people get angry [†¦and] turn to other bodies for protection, swelling the ranks of insurgent or organised crime groups. Corruption breeds inequality, which has been shown to increase violence† (Transparency International 2015). In Iraq, as previously discussed, ISIS was able to take†¦show more content†¦In reality, the only way to stop ISIS in Syria is to stop the Syrian civil war, and the best possible solution would be to remove President Assad from power. Although there would be backlash fro m Iran and Russia, this could be done simply by charging Assad, and his key supporters in government, with violations in Human Rights in the International Criminal Court, or the International Court of Justice. After he is taken out of power, negotiations can take place to determine the new government in Syria. When the US replaced the Hussein regime with a fully Shi’ite regime, they neglected to include any members from the previous regime, or any members from the Kurdish and Sunni populations. It is because of this why ISIS was able to flourish in Iraq; and the best way to undo this decision, is to also engage in negotiations. In both cases, negotiations would not take place between the Iraqi or Syrian government and ISIS; rather, they would take place between the governments and the chosen leaders of the oppressed groups (Sunni, Shi’ite, and Kurdish), in a neutral, private environment, such as the UN. The reason why ISIS will not be involved in negotiations is because they are escalating, radical terrorists who think that everything that the West, including what any of their adversaries, represents should be eliminated. ISIS will never be ripe for negotiation because â€Å"negotiation is appropriate when the parties see that a problem can onlyShow MoreRelatedIgbo Dictionary129408 Words   |  518 Pagesreplaced. It was originally prepared in Ibadan and some of the examples reflect this. Cultural and monetary references may well induce nostalgia in those familiar with the more recent history of Nigeria1. Web publication is therefore an intermediate step, while efforts are underway to produce an ac ceptable version for a press. Roger Blench Cambridge November 2006. 1 e.g. the example ‘The members of staff of the Kingsway stores enjoy life’ [!] i Igbo Dictionary: KayWilliamson. Draft of EditionRead MoreManaging Information Technology (7th Edition)239873 Words   |  960 PagesMidsouth Chamber of Commerce (A): The Role of the Operating Manager in Information Systems CASE STUDY I-1 IMT Custom Machine Company, Inc.: Selection of an Information Technology Platform CASE STUDY I-2 VoIP2.biz, Inc.: Deciding on the Next Steps for a VoIP Supplier CASE STUDY I-3 The VoIP Adoption at Butler University CASE STUDY I-4 Supporting Mobile Health Clinics: The Children’s Health Fund of New York City CASE STUDY I-5 Data Governance at InsuraCorp CASE STUDY I-6

Tone Interpretation for a Rose for Emily Free Essays

Teegan Brock Brad Nelson Luke Ziegler Trevor Magerowski Paul Reid English Comp 2 March 18, 2013 Insane Asylum for Emily The short story,† A Rose for Emily† written by William Faulkner has a distinct tone that helps depict the overall theme of how a woman unloved by her father falls into the dark treacherous depths of insanity. In the beginning of the story Emily lived with her father. Her father drove away all of the men in her life so she never found love. We will write a custom essay sample on Tone Interpretation for a Rose for Emily or any similar topic only for you Order Now Also her father was very overbearing and basically the only person that she ever grew to know personally. Her father cut her extended family off from her so she never was very social. Once her father died she was alone. She had no one except her servants and she was very lonely which probably drove her into partial insanity. She was very used to self-pity because her father was a very big man in the community so once he passed away she never had to pay taxes so she was basically exempt from society. After her father died she started to see more of people such as her cousins that her father drove away when she was alive. She found love in a guy named homer that went south after she found out about his homosexuality. Faulkner does a good job of using a dark tone and making Emily almost seem unsociable and unlovable to a point where nobody wants to be in her life. Homer basically was the straw that broke the camel’s back and drove her deep into insanity. After Emily finds out about her sexuality she goes to the store to buy poison. The tone in the story makes it near impossible to predict what she was going to do with the poison. The store keeper asked her what she needed it for and she refused to tell him and bought it anyway. She then bought a silver toilet set with her initials engraved on it and a complete outfit including a night shirt. This shows her insanity because she is buying him stuff when he clearly does not love her. This in turn might be the reason for her buying the arsenic because he left when the cousins came and she clearly was upset about it. Late in the story Emily’s house started to smell horrid and it was disturbing the community. Because, of her social status and her reputation for being the crazy, grumpy old lady the town refused to take action and disturb her. Thirty years passed the smell continued so the town just sprinkled lime to cover up the smell. After she passed away they went upstairs to her room and discovered homers dead body. This story and the overall tone clearly pleads the case of Emily’s insanity because they found her hair on the indented pillow lying next to homers body. This showed that she slept in the bed with him. She hid that body for 30 years and lived with the smell. The authors tone made it easy to depict the theme that Emily was drove into insanity by her father and never being able to find love and be social with other people. To quote the great W. C. Fields â€Å"No doubt exists that all women are crazy; it’s only a question of degree. † And in Emily’s case it’s the highest degree. How to cite Tone Interpretation for a Rose for Emily, Papers

Business Research Proposal Big Data Field †Free Samples

Question: Discuss about the Business Research Proposal Big Data Field. Answer: Introduction Throughout the most recent couple of years, information has turned out to be a standout amongst the most imperative resources for organisations in nearly each field. In addition to the fact that they are critical for organisations identified with the software engineering industry, however additionally for associations, for example, nations' medicinal services, governments, the building or instruction division. Information is fundamental regarding doing their day by day exercises, and furthermore helping the organisations' administration to accomplish their objectives and settle on the best choices on the premise of the data separated from them. It is assessed that of the considerable number of information in recorded mankind's history, 90% has been made over the most recent couple of years. In 2003, 5 exabytes of information were made by people, and this measure of data is, at present, made inside two days. This propensity towards expanding the volume and detail of the information th at is gathered by organisations won't change sooner rather than later, as the ascent of informal organisations, interactive media, and the Internet of Things is creating a mind-boggling stream of information. Project objective Keeping in mind the end goal to acquire a major photo of the security issue in the Big Data field, we chose to do an observational examination in light of past writing. We, in this manner, set out to receive the precise mapping study technique. Mapping contemplates substantially utilise an indistinguishable approach from (Assunoa et al., 2015). Orderly address audits, however, their principal target is to recognise and arrange all the examination identified with an expansive programming designing theme, instead of noting a more particular question. This strategy has four phases: the examination addresses, the exploration technique, the case choice and contextual investigation rules and strategies and, at last, information investigation and translation. Project scope Big Data is impacting IT industry like a couple of innovations have done some time recently. The huge information created from sensor-empowered machines, cell phones, distributed computing, web-based social networking, satellites help distinctive associations enhance their basic leadership and take their business to another level. Information is the greatest thing to hit the business since PC was concocted by Steve Jobs. As said before in this paper, consistently information is produced in such a fast way, to the point that, customary database and other information putting away framework will steadily surrender in putting away, recovering, and finding connections among information (Khan, Shakil and Alam, 2015). Huge information advancements have tended to the issues identified with this new huge information transformation using item equipment and conveyance. Organisations like Yahoo!, Google, General Electric, and Amazon. Facebook, Cornerstone, Kaggle, Microsoft that is putting a gre at deal in Big Data investigate and ventures. Literature review Manyika (2011) massive data is an idea, and an idea can have different translations, for which a similar subject can have numerous definitions, Huge Data is the measure of information past the capacity of innovation to store, oversee and prepare proficiently. Huge Data is a term which characterises the fast, hello there-tech, perplexing and multivariate high-volume, information to catch, store, convey, oversee and examine the data (TechAmerica Foundation, 2014). Grsakal Gartner (2014) stated that Enormous information is high volume, high speed, or potentially high assortment data resources that require new types of handling to empower improved basic leadership, process and understanding revelation enhancement Research questions For our situation, the inquiries incorporate the examination of the principle difficulties and issues that can be found regarding the subject of Big Data security, alongside another question whose goal is to find the principle security measurements on which scientists are centring their endeavours. At last, we wished to find which distinctive strategies, techniques or models have as of now been created so as to manage these problems. A meaning of the examination questions took after, and the inspiration was driving them. Primary question: what are the principle difficulties and issues about Big Data security? To inspire the primary issues and difficulties related to Big Data security. Secondary question: what are the principle security measurements on which are scientists centring their endeavours? To find what the primary concentration is for those Exploring Big Data security. What strategies, systems, and models with which to accomplish security in Big Data exist? To examine the different philosophies, models or strategies used to make Big Data frameworks secure (IEEE International Conference on Big Data, 2015). Research methodology and design The exploration strategy utilised was that of completing a programme inquiry of different on the web Libraries: SCOPUS, and ACM, the IEEE Digital Library. The explanation behind choosing these libraries rather than others was that they contain an incredible measure of writing identified with our fundamental goal and that they would encourage a particular inquiry. Keeping in mind the end goal to accomplish a legitimate result, we made an exploration string: Enormous Data OR Hadoop OR Big Data AND Secure OR Integrity OR Confidentiality OR Privacy OR Availability. The initial segment of the examination string is identified with Big Data innovation, in this way, incorporated the principle execution of Big Data. Hadoop can be considered as a true standard (Bhosale and Gadekar, 2014). The second some portion of the string is identified with the conventional security measurements: secrecy, honesty, and accessibility. We additionally chose to incorporate the protection measurement, despite t he fact that it can be considered as individual classification. This choice was identified with the bigger effect that the protection measurement appears to have as for the subject of Big Data in the examination with classification. This discernment is likewise affirmed by the grouping made by the CSA. Quantitative research Before beginning our examination, we chose to complete a little scan for studies so as to find whether there were any papers that had as of now managed the subject of our examination. This objective was expert via looking the same online libraries for papers checking on the security of Big Data between the years 2004 and 2015. We discovered a few audits concentrated on more particular themes, for example, protection in informal organisations, however, were not able to discover any whose goal was to acquire an abnormal state photo of the security in Big Data. The previously mentioned look into the string was then keep running in the chose online libraries all together scan for the words it contained in the titles, catchphrases, digests, and entire writings of papers. This brought about around 2300 papers. When we had acquired the papers that affirmed to our examination address, it was important to put forth a defence determination to achieve just those that best fit with our primary r esearch point (Li, 2013). With the end goal for us to keep up those that were truly identified with our exploration, the chose papers needed to satisfy various criteria, for example, having been distributed in the vicinity of 2004 and 2015. We moreover thought to be just those papers distributed in diaries, gatherings, congresses, or imperative workshop. Research limitation Each businessperson has been bothered by the term enormous information. On the off chance that any individual has not listened, huge information is viewed as the response to fruitful advertising these days. One marvels whether it will wind up being one of those administration fans they had got usual to have in the 1980's and 1990's, to be overlooked when they moved into the 2000's. In any case, enormous information is here with them, and they have to comprehend it since it has its advantages. Be that as it may, they might need to state at the beginning enormous information is insufficient. The idea is that by taking a gander at past buyer conduct, taking after customers as they peruse through the web, and investigating socioeconomics, advertisers trust that they can comprehend consumers completely. So the more information sources one has and the more the information can be incorporated, one would take in each of the ones has to think about buyer conduct. Somebody made the popular cla im nearly 8 years prior with enough information, the numbers represent themselves. Conclusion This paper gives a clarification of the examination completed keeping in mind the end goal to find the principle issues and difficulties identified with security in Big Data, and how analysts are managing these issues. This goal was accomplished by taking after the methodical mapping study strategy, which enabled us to discover the papers identified with our fundamental objective. Having done as such, we found that the main issues are identified with the inborn qualities of a Big Data framework, and furthermore to the way that security issues were not considered when Big Data was at first imagined. Many creators, accordingly, concentrate their examination on making intends to ensure information, especially regarding protection, however security it is by all account not the only security the issue that can be found in a Big Data framework; the conventional engineering itself and how to secure a Hadoop framework is additionally a colossal worry for the researchers. All in all, the Big Data innovation is by all accounts achieving to develop organise, and that is the motivation behind why there have been various reviews made the most recent year. Notwithstanding, that does not imply that it is no longer important to study this worldview. Indeed, the studies made from now ought to concentrate on more particular issues. Besides, Big Data can be valuable as a base for the advancement without bounds innovations that will change the world as they see it, similar to the Internet of Things, or on-request benefits, and that is the motivation behind why Big Data is, all things considered, what's to come. References Assunoa, M., Calheiros, R., Bianch, S., Netto, M. and Buyya, R. (2015). Big Data computing and clouds: Trends and future directions.J. Parallel Distrib. Comput.. [online] Available at: https://www.cloudbus.org/papers/BDC-Trends-JPDC.pdf [Accessed 22 May 2017]. Bhosale, H. and Gadekar, D. (2014). A Review Paper on Big Data and Hadoop.International Journal of Scientific and Research Publications, [online] 4(10). Available at: https://www.ijsrp.org/research-paper-1014/ijsrp-p34125.pdf [Accessed 22 May 2017]. IEEE International Conference on Big Data. (2015). [online] Available at: https://cci.drexel.edu/bigdata/bigdata2015/ProgramSchedulePDF.pdf [Accessed 22 May 2017]. Khan, S., Shakil, K. and Alam, M. (2015). CLOUD-BASED BIG DATA ANALYTICS A SURVEY OF CURRENT RESEARCH AND FUTURE DIRECTIONS. [online] Available at: https://arxiv.org/ftp/arxiv/papers/1508/1508.04733.pdf [Accessed 22 May 2017]. Li, B. (2013). Survey of Recent Research Progress and Issues in Big Data. [online] Available at: https://www.cse.wustl.edu/~jain/cse570-13/ftp/bigdata2.pdf [Accessed 22 May 2017].

Friday, May 1, 2020

Essential Skills for Leadership Effectiveness

Question: Discuss about the Essential Skills for Leadership Effectiveness. Answer: Introduction The project planning process is a balancing act of project constraints by providing decision making tools in line with the stakeholder objectives, performance targets, business practices and project goals. For successful project delivery, an organization needs to implement management systems that will guide the project scope, budgetary allocations, and risk mitigation. As business today become bigger and require more complex infrastructure requirements, management of copious amounts of data, employees and the day-to-day of business becomes a challenge to many companies. Moreover, in a tech savvy business environment, modern businesses have invested in network solutions to manage various departments sometimes spread out over different geographical locations (Project Management Institute, 2008). Project management approach Business Management Software is a set of tools aimed at streamlining strategic planning and tactical implementations of policies, practices, guidelines and procedures essential in the development, deployment and execution of business plans that supplement management. The functional groups of BMS is a goal-oriented hierarchy involving business management strategies, tactics and implementation guidelines. Implementation of a given BMS software package for an organization will be determined by its functionality, data integrity, testability, flexibility, cost and its integration with other systems. Moreover, a BMS software that will have minimal changes to the organizations current infrastructure setup will be a favorable option. This will be supported by a BMS maintenance crew and a project portfolio management service. Objectives The Department of Industry-Lands with the foregoing in mind, needs a BMS software package that offers network resources and various access permissions within the department managed based on the type of users, and the office locations. Furthermore, the BMS package should offer content management, FTP uploads and downloads, billing support and remote login. Offices will need to be automated and networked to ease flow of information and save on time taken to perform tasks. Scope and deliverables At the project pre-implementation stage, the project scope sets out clearly defined goals and needs of the project. In the case of The Department of Industry Lands (NSW), the department is accountable for about 41% of New South Wales crown land covering 35,000 crown reserves and government infrastructure totaling valued at about AUS $12 billion. Also, these shall form the scope of the project plan for the BMS software to be implemented(Department of Industry - Lands, 2014). Ideally, an assessment of the organizations preparedness for the BMS roll out by distinguishing the inherent strengths and weaknesses. Here, technical preparation uncovers the adequacy of the servers and software and a review of the IT department skills. This is followed by functional readiness where personnel experience is taken into account and factors such as leadership, communication and resources are updated. Then, the BMS software package appropriate for the organization is selected for subsequent implementation. The next stage involves finalizing the project scope, drafting the project organization structure and reporting guidelines are tabled. The realization phase the organization system is configured and developed and then tested or simulated to verify its functionality. Subsequently, a pre-go live audit is done to migrate all the organizations data to the new system and ensure it is well reconciled and operational. After this, a support phase is initiated to tackle issues arising from the go-live phase and the migration is stabilized(DZEMYDIEN BALTRUAITIS, 2015). Benefits The reason for a BMS software implementation is to ease an organizations business dealings. The lands department will accrue a number of benefits from the use of BMS software in the following ways. Firstly, the department will in the long run cut on operating costs through the use of electronic transaction, reduce workload on the employees and use resources more efficiently. Secondly, clients and even employees seeking information will receive accurate data in a timely fashion. Key milestones for procuring and implementing a BMS software package For the lands department leadership, the BMS software solution will present better control and facilitate informed decision making prospects. Moreover, the business process of handling leases and deeds will be rationalized, enabling efficient business dealings with clients. Since BMS software today offer computerized accounting, financial records will be easily consolidated at a click of a button and financial errors will be minimized. Cash flow management will also be more transparent and lease payments and land sales can be tracked. Furthermore, the quality of customer service will be enhanced as all client information and interactions with the department will be stored in a database. The department in this regard will provide customer specific products and services resulting in a higher customer satisfaction rate with the organization. Employee communication and dealings with business partners will be expedited further eliminating redundancies and miscommunication. High level communication strategy across a geographically diverse business The idea of a global village instigated by the internet and globalization have pushed businesses to operate on a global scale thus creating demand for Business Management Software capable of consolidating and managing business relations spread over large geographical locations. For a project manager, these dynamics make the implementation of a new project an involving and complex process (Chuang, Ph.D., 2013). As (Foong, 2014) stipulates, effective communication among stakeholders is a crucial factor to the success of any project management endeavor. Forty percent of projects fail to meet their objectives and half of these unsuccessful projects attribute their failure to ineffective communication. The communication strategy used should target the main players necessary for the realization of the BMS project scope and objectives. Stakeholders in our case will include employees in the department, clients and the state. Employees will need to be aware of any issues which might arise during its implementation and be able to mitigate them early before they turn into crises. Clients on the other hand will need information on how the changes will affect them, available services during the transition period and the benefits they will enjoy from the system revamp. Also, frequent management meetings, comprehensive management reports and organized project records go a long way in smoothing communication between stakeholders and project team members. Project governance This constitutes a management framework adopted by the project management team to serve as a blueprint on which capital investment decisions are made. These decisions should be logical, robust and replicable structured approach in any project investment. For the lands department, the effective model will follow the four core principles of project governance (Mller, 2009). The project managements primary responsibility is to establish a central point of accountability for the BMS software roll out. This will guarantee a single person to solve the difficult decisions crucial at the initiation phase. This individual must hold significant authority and aptly empowered to carry the days decisions and position the project towards success. Secondly, project ownership is assigned to a specialist party to deter wasteful scope inclusions by the leadership. The third principle advocates for the isolation of project decision making activities and the stakeholder management. Stakeholder management in government institutions is usually multifaceted and vast thus diminishing the understanding of critical project issues and consequently affecting quality decision making. Lastly, institutional governance structures should be distinguished from the project governance structures. This is because the bureaucratic mechanisms inherent in organizational structure will get in the way of flexible and swift decision making associated with projects (Association for Project Management, 2004). Risks and mitigation In project management, it is the process of enhancing opportunities for the organization whilst reducing impending threats to project goals by developing viable options and suitable actions beforehand. Being an iterative process, it embarks on risk identification, assessment of the risk impact, risk prioritization analysis and finally risk mitigation (International Council on Systems Engineering (INCOSE), 2010). In the lands department, the project management team collaborates with the operational users of the BMS software to form a common understanding of risks and their consequences. Mechanisms to avoid risks are also outlined to improve performance or efficiency. Mitigation plans will seek to understand the needs of BMS software users, seek experts to solve the risks, recognize recurrent risks and evaluate the impact of each action with respect to project objectives. Sponsor Acceptance Approved by the Project Sponsor: Date: Name: sign: References Association for Project Management. (2004). Directing Change - A guide to governance of project management. Chuang, Ph.D., S.-F. (2013). essential skills for leadership effectiveness in diverse. Online Journal for Workforce Education and Development, 6(1). Retrieved from https://www.google.com/url?sa=trct=jq=esrc=ssource=webcd=10cad=rjauact=8ved=0ahUKEwjQufHygL_OAhXLWRoKHbWxAEwQFghZMAkurl=http%3A%2F%2Fopensiuc.lib.siu.edu%2Fcgi%2Fviewcontent.cgi%3Farticle%3D1133%26context%3Dojwedusg=AFQjCNFVJYp8PfCu8lSIFA7shUU00 Department of Industry - Lands. (2014). Comprehensive review of NSW Crown Land Management. Retrieved from www.crownland.nsw.gov.au: https://www.crownland.nsw.gov.au/crown_lands/comprehensive_review_of_nsw_crown_land_management Dzemydien, D., Baltruaitis, R. (2015). Evaluation of Functionality of Business Management Systems for Effective Implementation in Complex Business Processes. Baltic J. Modern Computing,, 179-192. Foong, M. Y. (2014, April 9). Effective Communication: A Challenge To Project Managers. Retrieved from www.projecttimes.com: https://www.projecttimes.com/articles/effective-communication-a-challenge-to-project-managers.html International Council on Systems Engineering (INCOSE). (2010). INCOSE Systems Engineering Handbook. Lewinson, M. (2010). Business Management System (BMS) Definition and Functional Groups. My Management Guide. Retrieved from www.mymanagementguide.com: https://www.mymanagementguide.com/business-management-system-bms-definition-and-functional-groups/. Mller, R. (2009). Project Governance. Aldershot, UK: Gower Publishing. Project Management Institute. (2008). A Guide to the Project Management Body of Knowledge, (PMBOK Guide) (Fourth Edition ed.).